A private Catholic liberal-arts college in downtown Wilkes-Barre. It was founded 1946, operated by the Congregation of Holy Cross, and offers undergraduate and graduate programs. 

A private university in Wilkes-Barre, offering liberal arts, professional, and graduate programs. Founded in 1933 (as a junior college), and attained university status in 1990.

A publicly supported two-year community college serving the region around Wilkes-Barre. Offers Associate degrees, certificates, and workforce training programs.